{"id":757,"date":"2026-07-31T10:12:31","date_gmt":"2026-07-31T02:12:31","guid":{"rendered":"http:\/\/www.ziypeptide.com\/?post_type=product&#038;p=757"},"modified":"2026-07-31T10:15:54","modified_gmt":"2026-07-31T02:15:54","slug":"ca20","status":"publish","type":"product","link":"https:\/\/www.ziypeptide.com\/index.php\/product\/ca20\/","title":{"rendered":"Cardiogen"},"content":{"rendered":"<p>Cardiogen is supplied as a laboratory research reference material intended solely for in-vitro and laboratory research use. The item is a synthetic tetrapeptide comprising four residues in the sequence Ala-Glu-Asp-Arg (single-letter: AEDR), corresponding to the empirical molecular formula C17H30N8O8 and a calculated monoisotopic-consistent average molecular weight of approximately 474.5 g\/mol. The primary structure combines a nonpolar N-terminal alanine, two acidic residues (glutamic acid and aspartic acid) contributing free side-chain carboxylates, and a C-terminal arginine bearing a strongly basic guanidinium group, giving Cardiogen a distinctive zwitterionic character with multiple ionizable sites across a broad pH range.<\/p>\n<p>At neutral pH the peptide is expected to carry both anionic (Glu, Asp side chains and C-terminal carboxylate) and cationic (Arg guanidinium and N-terminal amine) functionalities, which is relevant to solubility screening, buffer selection, and chromatographic retention. This ionic profile typically favors aqueous solubility and makes Cardiogen a useful reference for reversed-phase HPLC method development, ion-pair chromatography, capillary electrophoresis, and mass spectrometry workflows where short, highly polar peptides can be challenging analytes. Expected charge-state envelopes under positive-mode electrospray commonly include the singly and doubly protonated species, consistent with the amino-acid composition.<\/p>\n<p>Cardiogen is produced by chemical synthesis (Source: Synthetic), isolated as a lyophilized powder, and presented as a white to off-white cake or amorphous solid. Purity is specified as not less than 98% by HPLC, with the identity, chromatographic purity, and supporting analytical data (typically including mass confirmation) documented on the lot-specific Certificate of Analysis, available on request. The catalog identifier for this item is SKU CARDIOGEN, which researchers can reference when correlating experimental records with lot documentation.<\/p>\n<p>Published scientific literature has examined Cardiogen (Ala-Glu-Asp-Arg) in preclinical research contexts, and the peptide is frequently cited alongside other short regulatory-oligopeptide reference standards used for in-vitro characterization, analytical method qualification, and structure-property comparison studies. As with all short peptides, laboratory handling should account for hygroscopicity of the lyophilizate, potential deamidation at Asn\/Gln-adjacent chemistries (not applicable here) and the general recommendation to store the sealed vial cold and protected from moisture prior to reconstitution in a compatible research-grade solvent for analytical work.<\/p>\n<p>PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding Cardiogen and provides no administration or dosing guidance. This material is not a drug, supplement, cosmetic, or food, and is not intended for human or veterinary use, injection, or ingestion. It is offered exclusively as a characterized reference material to qualified investigators for in-vitro and laboratory research applications.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cardiogen is supplied as a laboratory research reference material intended solely for in-vitro and laboratory research use. The item is a synthetic tetrapeptide comprising four residues in the sequence Ala-Glu-Asp-Arg (single-letter: AEDR), corresponding to the empirical molecular formula C17H30N8O8 and a calculated monoisotopic-consistent average molecular weight of approximately 474.5 g\/mol. The primary structure combines a nonpolar N-terminal alanine, two acidic residues (glutamic acid and aspartic acid) contributing free side-chain carboxylates, and a C-terminal arginine bearing a strongly basic guanidinium group, giving Cardiogen a distinctive zwitterionic character with multiple ionizable sites across a broad pH range.<\/p>\n","protected":false},"featured_media":749,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[25],"product_tag":[],"class_list":["post-757","product","type-product","status-publish","has-post-thumbnail","product_cat-medication","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/product\/757","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/comments?post=757"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/media\/749"}],"wp:attachment":[{"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/media?parent=757"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/product_brand?post=757"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/product_cat?post=757"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/product_tag?post=757"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}