{"id":771,"date":"2026-07-31T10:32:32","date_gmt":"2026-07-31T02:32:32","guid":{"rendered":"http:\/\/www.ziypeptide.com\/?post_type=product&#038;p=771"},"modified":"2026-07-31T10:45:02","modified_gmt":"2026-07-31T02:45:02","slug":"melanotan-ii","status":"publish","type":"product","link":"https:\/\/www.ziypeptide.com\/index.php\/product\/melanotan-ii\/","title":{"rendered":"Melanotan II"},"content":{"rendered":"<p>Melanotan II is supplied as a laboratory research reference material intended solely for in-vitro and laboratory research use. This synthetic cyclic heptapeptide is defined by the amino-acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2, in which an N-terminal acetyl cap and a C-terminal primary amide flank a lactam bridge formed between the side-chain carboxyl of Asp and the epsilon-amine of Lys. The Nle (norleucine) substitution at position 4 and the D-Phe stereoinversion at position 7 are hallmark structural modifications relative to the parent alpha-MSH core sequence His-Phe-Arg-Trp, and are of interest as reference features in comparative peptide chemistry studies.<\/p>\n<p>The compound is registered under CAS 121062-08-6 and PubChem CID 92432, with molecular formula C50H69N15O9, average molecular weight 1024.18 g\/mol, and monoisotopic mass 1023.5403 Da. The canonical SMILES string CCCCC(C(=O)NC1CC(=O)NCCCCC(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CC2=CN=CN2)CC3=CC=CC=C3)CCCN=C(N)N)CC4=CNC5=CC=CC=C54)C(=O)N)NC(=O)C and InChIKey JDKLPDJLXHXHNV-MFVUMRCOSA-N provide unambiguous identifiers for cheminformatics workflows, database cross-referencing, and analytical method development involving Melanotan II.<\/p>\n<p>Physically, Melanotan-II (catalog SKU: Melanotan-II) is presented as a white to off-white lyophilized powder of synthetic origin. Purity is specified as not less than 98% by HPLC, with lot-specific chromatographic, mass-spectrometric, and appearance data captured on the Certificate of Analysis available on request. The 27-atom macrocycle and the presence of aromatic (His, D-Phe, Trp) and basic (Arg) side chains give the molecule a distinctive UV profile useful in reversed-phase HPLC detection, while the monoisotopic mass of 1023.5403 Da supports confirmation by high-resolution ESI-MS.<\/p>\n<p>Published scientific literature has examined Melanotan II in preclinical research contexts, and the material is offered here strictly to support qualified laboratory investigators requiring a well-characterized analytical reference. PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding Melanotan II and provides no administration or dosing guidance of any kind. This material is not a drug, supplement, cosmetic, or food, and is not intended for human or veterinary use, injection, or ingestion. Identity, purity, and lot-specific characterization data are documented on the Certificate of Analysis, available on request.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Melanotan II is supplied as a laboratory research reference material intended solely for in-vitro and laboratory research use. This synthetic cyclic heptapeptide is defined by the amino-acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2, in which an N-terminal acetyl cap and a C-terminal primary amide flank a lactam bridge formed between the side-chain carboxyl of Asp and the epsilon-amine of Lys. The Nle (norleucine) substitution at position 4 and the D-Phe stereoinversion at position 7 are hallmark structural modifications relative to the parent alpha-MSH core sequence His-Phe-Arg-Trp, and are of interest as reference features in comparative peptide chemistry studies.<\/p>\n","protected":false},"featured_media":728,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[25],"product_tag":[],"class_list":["post-771","product","type-product","status-publish","has-post-thumbnail","product_cat-medication","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/product\/771","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/comments?post=771"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/media\/728"}],"wp:attachment":[{"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/media?parent=771"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/product_brand?post=771"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/product_cat?post=771"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.ziypeptide.com\/index.php\/wp-json\/wp\/v2\/product_tag?post=771"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}