ARA-290 (Cibinetide)

ARA-290 (CAS 1208243-50-8) is offered by PEPTIDE.Power as a synthetic laboratory research reference material intended strictly for in-vitro and laboratory research use. As an 11-residue linear peptide derived from the aqueous-exposed helix B region of erythropoietin, ARA-290 belongs to the class of non-erythropoietic EPO-mimetic sequences frequently used as reference standards in peptide characterization workflows.

The material is defined by the molecular formula C49H72N14O18 and a monoisotopic/average molecular weight of approximately 1257 g/mol, providing a distinctive mass signature for LC-MS and MALDI-TOF confirmation. Its declared amino-acid sequence is PHBSPGDKQTNS, corresponding to Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser, and the item is cataloged under SKU ARA-290. The N-terminal pyroglutamate (Pyr-Glu) cap is a notable structural feature that eliminates a free alpha-amino group at that position, which analysts should account for when planning Edman degradation, N-terminal labeling, or ion-pair reversed-phase HPLC method development. Multiple acidic (Glu), basic (Arg, Lys), and polar hydroxyl-bearing (Ser, Thr, Asn) residues contribute to a mixed hydrophilic character relevant to solubility screening and buffer compatibility studies.

Physically, ARA-290 is supplied as a white to off-white lyophilized powder produced by solid-phase peptide synthesis, with purity specified at not less than 98% by HPLC and confirmed on a lot-specific Certificate of Analysis available on request. The CoA typically documents identity by mass spectrometry, purity by reversed-phase HPLC, appearance, and related quality attributes, supporting traceability for comparative reference work, assay calibration, method qualification, and analytical benchmarking against in-house or third-party ARA-290 lots.

Published scientific literature has examined ARA-290 in preclinical research contexts, and this listing is provided solely to describe the compound’s chemistry and analytical identity. PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding ARA-290 and provides no administration, formulation, or dosing guidance of any kind.

This material is not a drug, dietary supplement, cosmetic, or food. It is not intended or suitable for human or veterinary use, injection, ingestion, topical application, or any in-vivo administration, and should be handled exclusively by qualified personnel within an appropriately equipped research laboratory under applicable institutional and regulatory guidelines.