MOTS-c

MOTS-c is supplied as a laboratory research reference material intended solely for in-vitro and laboratory research use. The item is a synthetic 16-residue peptide corresponding to the sequence Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (one-letter: MRWQEMGYIFYPRKLR), assigned CAS 1415585-49-1, with a molecular formula of C136H224N38O38 and a calculated monoisotopic-consistent average molecular weight of approximately 2172.6 g/mol.

From a compositional standpoint, MOTS-c contains a mixture of hydrophobic (Met, Trp, Ile, Phe, Leu, Tyr), basic (two Arg, one Lys), acidic (Glu), polar-uncharged (Gln, Tyr), and conformationally restrictive (Pro, Gly) residues, giving the sequence a net positive charge at neutral pH. The presence of two internal methionines and one tryptophan makes the material a useful reference for studying oxidation-sensitive residues during handling and analytical workups, while the paired tyrosines and single tryptophan provide characteristic UV absorbance around 274-280 nm that is convenient for spectrophotometric identity checks and concentration estimation in research settings.

Physically, MOTS-c is provided as a white to off-white lyophilized powder produced by chemical synthesis (solid-phase peptide synthesis workflows), with purity of not less than 98% as determined by reversed-phase HPLC. Identity is typically confirmed by mass spectrometry consistent with the C136H224N38O38 composition, and both identity and purity values are documented on the lot-specific Certificate of Analysis, available on request. The lyophilized format supports reconstitution in laboratory solvents chosen by the investigator for their specific analytical, chromatographic, or reference-standard application.

Published scientific literature has examined MOTS-c in preclinical, cell-based, and biochemical research contexts, and its mitochondrial-derived 16-amino-acid peptide profile has made it a recurring subject of characterization studies. PEPTIDE.Power provides this material strictly as a chemical reference standard and makes no therapeutic, diagnostic, or efficacy claims regarding MOTS-c, nor any administration, dosing, formulation, or handling guidance for living subjects. This material is not a drug, dietary supplement, cosmetic, or food ingredient, and it is not intended for human or veterinary use, injection, ingestion, topical application, or any in-vivo purpose.