Cardiogen

Cardiogen is supplied as a laboratory research reference material intended solely for in-vitro and laboratory research use. The item is a synthetic tetrapeptide comprising four residues in the sequence Ala-Glu-Asp-Arg (single-letter: AEDR), corresponding to the empirical molecular formula C17H30N8O8 and a calculated monoisotopic-consistent average molecular weight of approximately 474.5 g/mol. The primary structure combines a nonpolar N-terminal alanine, two acidic residues (glutamic acid and aspartic acid) contributing free side-chain carboxylates, and a C-terminal arginine bearing a strongly basic guanidinium group, giving Cardiogen a distinctive zwitterionic character with multiple ionizable sites across a broad pH range.

At neutral pH the peptide is expected to carry both anionic (Glu, Asp side chains and C-terminal carboxylate) and cationic (Arg guanidinium and N-terminal amine) functionalities, which is relevant to solubility screening, buffer selection, and chromatographic retention. This ionic profile typically favors aqueous solubility and makes Cardiogen a useful reference for reversed-phase HPLC method development, ion-pair chromatography, capillary electrophoresis, and mass spectrometry workflows where short, highly polar peptides can be challenging analytes. Expected charge-state envelopes under positive-mode electrospray commonly include the singly and doubly protonated species, consistent with the amino-acid composition.

Cardiogen is produced by chemical synthesis (Source: Synthetic), isolated as a lyophilized powder, and presented as a white to off-white cake or amorphous solid. Purity is specified as not less than 98% by HPLC, with the identity, chromatographic purity, and supporting analytical data (typically including mass confirmation) documented on the lot-specific Certificate of Analysis, available on request. The catalog identifier for this item is SKU CARDIOGEN, which researchers can reference when correlating experimental records with lot documentation.

Published scientific literature has examined Cardiogen (Ala-Glu-Asp-Arg) in preclinical research contexts, and the peptide is frequently cited alongside other short regulatory-oligopeptide reference standards used for in-vitro characterization, analytical method qualification, and structure-property comparison studies. As with all short peptides, laboratory handling should account for hygroscopicity of the lyophilizate, potential deamidation at Asn/Gln-adjacent chemistries (not applicable here) and the general recommendation to store the sealed vial cold and protected from moisture prior to reconstitution in a compatible research-grade solvent for analytical work.

PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding Cardiogen and provides no administration or dosing guidance. This material is not a drug, supplement, cosmetic, or food, and is not intended for human or veterinary use, injection, or ingestion. It is offered exclusively as a characterized reference material to qualified investigators for in-vitro and laboratory research applications.