Melanotan II

Melanotan II is supplied as a laboratory research reference material intended solely for in-vitro and laboratory research use. This synthetic cyclic heptapeptide is defined by the amino-acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2, in which an N-terminal acetyl cap and a C-terminal primary amide flank a lactam bridge formed between the side-chain carboxyl of Asp and the epsilon-amine of Lys. The Nle (norleucine) substitution at position 4 and the D-Phe stereoinversion at position 7 are hallmark structural modifications relative to the parent alpha-MSH core sequence His-Phe-Arg-Trp, and are of interest as reference features in comparative peptide chemistry studies.

The compound is registered under CAS 121062-08-6 and PubChem CID 92432, with molecular formula C50H69N15O9, average molecular weight 1024.18 g/mol, and monoisotopic mass 1023.5403 Da. The canonical SMILES string CCCCC(C(=O)NC1CC(=O)NCCCCC(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CC2=CN=CN2)CC3=CC=CC=C3)CCCN=C(N)N)CC4=CNC5=CC=CC=C54)C(=O)N)NC(=O)C and InChIKey JDKLPDJLXHXHNV-MFVUMRCOSA-N provide unambiguous identifiers for cheminformatics workflows, database cross-referencing, and analytical method development involving Melanotan II.

Physically, Melanotan-II (catalog SKU: Melanotan-II) is presented as a white to off-white lyophilized powder of synthetic origin. Purity is specified as not less than 98% by HPLC, with lot-specific chromatographic, mass-spectrometric, and appearance data captured on the Certificate of Analysis available on request. The 27-atom macrocycle and the presence of aromatic (His, D-Phe, Trp) and basic (Arg) side chains give the molecule a distinctive UV profile useful in reversed-phase HPLC detection, while the monoisotopic mass of 1023.5403 Da supports confirmation by high-resolution ESI-MS.

Published scientific literature has examined Melanotan II in preclinical research contexts, and the material is offered here strictly to support qualified laboratory investigators requiring a well-characterized analytical reference. PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding Melanotan II and provides no administration or dosing guidance of any kind. This material is not a drug, supplement, cosmetic, or food, and is not intended for human or veterinary use, injection, or ingestion. Identity, purity, and lot-specific characterization data are documented on the Certificate of Analysis, available on request.